Cat. No. | Product Name | Target | Signaling Pathways |
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TP1244L1 |
Adrenocorticotropic Hormone (ACTH) (1-10), human acetate
Adrenocorticotropic Hormone (ACTH) (1-10), human acetate(2791-05-1 Free base) |
Others | Others |
Adrenocorticotropic Hormone (ACTH) (1-10), human acetate 是促肾上腺皮质激素的一个片段。 Adrenocorticotropic Hormone (ACTH) (1-10), human acetate 仅在 100 和 1000 nM 时具有较弱的 α-MSH 效力。 | |||
T8231 |
Adrenocorticotropic Hormone (ACTH) (1-39), human
ACTH (1-39), human,丝拉克肽 |
Others | Others |
Adrenocorticotropic Hormone (ACTH) (1-39), human (ACTH (1-39), human) 是黑皮质素受体激动剂。 | |||
TP1240 |
Adrenocorticotropic Hormone (ACTH) (18-39), human TFA
CLIP (human) (TFA) |
Others | Others |
Adrenocorticotropic Hormone (ACTH) (18-39), human TFA (CLIP human TFA) 是一种似皮质促素中叶肽,由垂体中叶的促黑素细胞产生。 | |||
TP1244 |
Adrenocorticotropic Hormone (ACTH) (1-10), human
ACTH (1-10), human |
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Adrenocorticotropic Hormone (ACTH) (1-10), human is a fragment of the adrenocorticotropin hormone. It exhibits a weak potency of α-melanocyte stimulating hormone (α-MSH), but only at high doses (100 and 1000 nM). | |||
T7627 |
Adrenocorticotropic Hormone (ACTH) (4-10), human
Adrenocorticotropic Hormone (ACTH) (4-10),ACTH (4-10), human,Acth (4-10) |
Melanocortin Receptor | GPCR/G Protein; Neuroscience |
Adrenocorticotropic Hormone (ACTH) (4-10), human 是黑皮质素 4 型受体 (melanocortin 4 receptor, MC4R) 激动剂。 | |||
TP1241 |
Adrenocorticotropic Hormone (ACTH) (18-39), human
ACTH (18-39), human |
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Adrenocorticotropic Hormone (ACTH) (18-39) is known as the Corticotropin-like Intermediate Lobe Peptide. It stimulates insulin secretion as well as amylase and protein secretion in a dose-dependent manner similar to those of secretin and carbamylcholine. | |||
TP1245 |
ACTH (4-11)
ACTH 4-11,Adrenocorticotropic Hormone (4-11), human |
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ACTH (4-11) is a peptide fragment of adrenocorticotropic hormone, a peptide hormone found in the brain that is involved in the biological stress response. | |||
TP1242 |
1-39-Corticotropin (human)(TFA)
Adrenocorticotropic Hormone (ACTH) (1-39), human(TFA) |
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Adrenocorticotropic Hormone (ACTH) (1-39) human(TFA),a member of the melanocortin family, is a melanocortin receptor agonist. It stimulates production of CS by the adrenals, but melanocortin receptors are also found in the central nervous system (CNS) and | |||
T80125 |
ACTH (7-38) (human)
|
Melanocortin Receptor | GPCR/G Protein; Neuroscience |
ACTH (7-38) (human) 是 ACTH (1-39) 的第7至第38个氨基酸序列构成的片段。该化合物作为ACTH受体的拮抗剂,又称为促肾上腺皮质激素抑制肽(CIP),它不具有皮质类固醇活性。 | |||
T83178 |
ACTH (6-24) (human)
Adrenocorticotropic hormone (6-24) |
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ACTH (6-24) (human)(腎上腺皮質激素(6-24))是腎上腺皮質激素的片段。該化合物作為ACTH (1-39) 和 ACTH (5-24) 引起的類固醇生成的競爭性抑制劑,具有相應的Kd值分別為13.4和3.4nM。此外,ACTH (6-24) (human) 能夠抑制 hPTH 1-34 所誘導的皮質酮產生以及cAMP的累積。 | |||
T76643 |
Acetyl-ACTH (3-24) (human, bovine, rat)
|
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Acetyl-ACTH (3-24) (human, bovine, rat) 是原黑色素皮质素 (POMC) 肽的片段。POMC 肽,如促肾上腺皮质激素(ACTH),是α-MSH 的前体,也是 MC-1 受体的激动剂。 | |||
T76642 |
Acetyl-ACTH (2-24) (human, bovine, rat)
|
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Acetyl-ACTH (2-24) (human, bovine, rat) 是原黑色素皮质素 (POMC) 肽的片段。POMC 肽,如促肾上腺皮质激素(ACTH),是α-MSH 的前体,也是MC-1受体的激动剂。 | |||
T76646 |
Acetyl-ACTH (7-24) (human, bovine, rat)
|
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Acetyl-ACTH (7-24) (human, bovine, rat) 可导致 ACTH 诱发的皮质酮和醛固酮释放显著减少。 | |||
T76644 |
Acetyl-ACTH (4-24) (human, bovine, rat)
|
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Acetyl-ACTH (4-24) (human, bovine, rat) 是原黑色素皮质素 (POMC) 肽的片段。POMC 肽,如促肾上腺皮质激素(ACTH),是α-MSH 的前体,也是 MC-1受体的激动剂。 | |||
T76595 |
(Des-His6)-ACTH (1-24) (human, bovine, rat)
|
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(Des-His6)-ACTH (1-24) (human, bovine, rat) 是促肾上腺皮质激素 (ACTH) 的类似物。ACTH 是一种由垂体前叶腺产生的多肽激素,调节皮质醇和雄激素的产生。 | |||
T76591 |
(Des-Glu5)-ACTH (1-24) (human, bovine, rat)
|
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(Des-Glu5)-ACTH (1-24) (human, bovine, rat) 是促肾上腺皮质激素 (ACTH) 的类似物。ACTH 是一种由垂体前叶腺产生的多肽激素,调节皮质醇和雄激素的产生。 | |||
T76500 |
ACTH (3-24) (human, bovine, mouse, ovine, porcine, rabbit, rat)
|
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ACTH (3-24) (human, bovine, mouse, ovine, porcine, rabbit, rat) 是ACTH的3-24片段,适用于癌症、免疫疾病、心血管疾病等多种疾病的研究。 | |||
TP1011L |
ACTH (1-17) acetate
|
Melanocortin Receptor | GPCR/G Protein; Neuroscience |
ACTH (1-17) acetate 是一种有效的人黑皮质素 1 (MC1) 受体激动剂,具有高亲和力 (Ki = 0.21 nM)。 | |||
T36926L |
Neuropeptide SF (human) aceate
|
Others | Others |
Neuropeptide SF (human) aceate 是一种神经肽,可增强心室旁 CRH 的释放并增加血浆中的 ACTH 和皮质酮水平。 | |||
TP2082L |
d[Cha4]-AVP acetate(500170-27-4 free base)
|
Vasopressin Receptor | GPCR/G Protein |
d[Cha4]-AVP acetate(500170-27-4 free base) 是一种有效的选择性人血管加压素 V1B 受体激动剂(V1B、V1A、催产素和 V2 受体的 Ki 值分别为 1.2、151、240 和 750 nM)。刺激 ACTH 和皮质酮分泌,并在体内表现出微不足道的血管加压活性。 | |||
TP1010 |
ACTH (1-17) (TFA) (7266-47-9 free base)
α1-17-ACTH TFA,ACTH (1-17) (TFA) |
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ACTH (1-17) TFA is a corticotrophin analogue and an effective human melanocortin 1 (MC1) receptor agonist with Ki value of 0.21 nM. | |||
TP1011 |
ACTH (1-17)
α1-17-ACTH |
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ACTH (1-17), an adrenocorticotropin analogue, is a potent human melanocortin 1 (MC1) receptor agonist with a Ki of 0.21 nM. Adrenocorticotropic hormone (ACTH), also known as corticotropin, is produced and secreted by the anterior pituitary gland. | |||
T76503 |
Defensin NP-3A
|
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Defensin NP-3A (NP-3A; Corticostatin 1) 是一种人粒细胞肽,具有抗 ACTH 活性。防御素是一种具有杀伤活性的抗菌肽。 | |||
TP1144 |
Corticotropin-releasing factor (human)
Human corticotropin-releasing factor,Human CRF,Corticotropin-releasing factor human |
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Corticotropin-releasing factor human (Human CRF; Human corticotropin-releasing factor) is an immunomodulatory neuropeptide that acts to release ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla. Functions b | |||
T75977 |
ACTH (1-17) (TFA)
|
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ACTH (1-17) TFA 是促肾上腺皮质激素类似物,是一种有效的人黑皮素受体 (human melanocortin 1 (MC1) receptor) 激动剂,Ki 值为 0.21 nM。 | |||
TP2082 |
d[Cha4]-AVP
|
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Potent and selective human vasopressin V1B receptor agonist (Ki values are 1.2, 151, 240 and 750 nM for V1B, V1A, Oxytocin and V2 receptors respectively). Stimulates ACTH and corticosterone secretion and exhibits negligible vasopressor activity in vivo. | |||
T76361 |
[DPro5] Corticotropin Releasing Factor, human, rat
|
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[DPro5] Corticotropin Releasing Factor, human, rat 是人类和大鼠促肾上腺皮质激素释放因子/激素 R2 的选择性激动剂。作为一种下丘脑激素,促肾上腺皮质激素释放因子 (CRF) 能够促进肾上腺皮质激素 (ACTH) 和 β-内啡肽的分泌。值得注意的是,[DPro5] Corticotropin Releasing Factor, human, rat 并不触发典型的焦虑反应,而是能调控大鼠的学习与记忆过程。 | |||
T75849 |
Lys-γ3-MSH(human) TFA
|
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Lys-γ3-MSH(human) TFA是源自POMC片段C端的黑素皮质素肽,具备增强大鼠肾上腺对促肾上腺皮质激素(ACTH)的类固醇生成反应的能力。该化合物作为一种有效的脂解激活剂,其表观EC50值为3.56 nM,能够激活激素敏感脂肪酶(HSL)和紫苏脂素A,进而促进脂解。 |